Nicholas Lukacs

Bio

Nicholas W. Lukacs, Ph.D. is the Godfrey D. Stobbe Professor of Pathology at the University of Michigan Medical School in Ann Arbor, Michigan. He received his Ph.D. from Wayne State University in 1992 and was first appointed as a faculty member at the University of Michigan in 1994. He is presently the Scientific Director of the Mary H Weiser Food Allergy Center at the University of Michigan Medical School. The Lukacs Lab research has previously examined leukocyte migration and chemokine biology during acute and chronic inflammatory diseases. The lab research is presently focused on the innate and acquired immune responses in allergen- and respiratory virus-induced diseases, as well as the role that the gut microbiome has on development of the early life immune system. These areas include function and activation of DC and T cells during infections and the differential epigenetic and transcriptional modulation of immune cell responses that lead to exacerbated disease progression. Translational collaborations include studies examining severe respiratory syncytial virus (RSV)-induced disease with infants in the Pediatric ICU as well as the development of food and airborne allergen responses in inner city birth cohorts linked to alterations in microbiome and metabolite profiles. In addition to research, he spends a significant amount of time mentoring Faculty and Trainees as PI of a NHLBI post-doctoral T32 training grant, with his work with the University of Michigan CTSI grant, and as a member of numerous thesis and faculty mentoring committees. He is presently Associate Editor for Mucosal Immunology and JCI Insight as well as past-President for the Society of Leukocyte Biology.